Terminology Service for NFDI4Health
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CARS/ALK Fusion Gene

Go to external page http://purl.obolibrary.org/obo/NCIT_C99871

A fusion gene that results from a chromosomal translocation t(2;11)(p23;p15) which fuses most of the CARS gene with the last ten exons of the ALK gene. This fusion is associated with both inflammatory myofibroblastic tumors and anaplastic large cell lymphoma. [ ]

Term info

Label

CARS/ALK Fusion Gene

Synonyms
  • ALK/CARS Fusion Gene
  • CARS-ALK Fusion Gene
  • CARS/ALK Fusion Gene
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

OMIM states that the cause of this gene fusion is a complex translocation t(2;11;2)(p23;p15;q31).

Display Name

CARS/ALK Fusion Gene

Preferred Name

CARS/ALK Fusion Gene

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C38184, http://purl.obolibrary.org/obo/NCIT_C97369

Semantic Type

Gene or Genome

UMLS CUI

C3151473

code

C99871