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CARS/ALK Fusion Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C99872

A fusion protein (680 aa, ~75 kDa) that is encoded by the CARS/ALK fusion gene. This protein contains 606 amino acids from the N-terminus of the cysteinyl-tRNA synthetase, cytoplasmic protein and the cytoplasmic domain of the ALK tyrosine kinase receptor protein. [ ]

Term info

Label

CARS/ALK Fusion Protein

Synonyms
  • CARS-ALK Fusion Protein
  • CARS/ALK Fusion Protein
  • Cysteinyl--tRNA Synthetase, Cytoplasmic/ALK Tyrosine Kinase Receptor Fusion Protein
  • Cysteinyl-tRNA Synthetase, Cytoplasmic/ALK Tyrosine Kinase Receptor Fusion Protein
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

The CARS/ALK fusion protein is a constitutively dimerized and activated tyrosine kinase.

Display Name

CARS/ALK Fusion Protein

Preferred Name

CARS/ALK Fusion Protein

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C38184, http://purl.obolibrary.org/obo/NCIT_C97369

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C3275010

code

C99872