Terminology Service for NFDI4Health
CLTC/ALK Fusion Gene
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http://purl.obolibrary.org/obo/NCIT_C99873
A fusion gene that results from a chromosomal translocation t(2;17)(p23;q23) which fuses the first 31 exons of the CLTC gene with the last ten exons of the ALK gene. This fusion is associated with both anaplastic large cell lymphoma and inflammatory myofibroblastic tumors. [ ]
Term info
Label
CLTC/ALK Fusion Gene
Synonyms
- ALK/CLTC Fusion Gene
- CLTC-ALK Fusion Gene
- CLTC/ALK Fusion Gene
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
Display Name
CLTC/ALK Fusion Gene
Preferred Name
CLTC/ALK Fusion Gene
Related To Genetic Biomarker
http://purl.obolibrary.org/obo/NCIT_C38184, http://purl.obolibrary.org/obo/NCIT_C97412
Semantic Type
Gene or Genome
UMLS CUI
C3151474
code
C99873
Term relations
Subclass of:
- Fusion Gene
- Gene_Plays_Role_In_Process some Tyrosine Phosphorylation
- Gene_Involved_In_Pathogenesis_Of_Disease some Anaplastic Large Cell Lymphoma, ALK-Positive
- Gene_Involved_In_Pathogenesis_Of_Disease some Inflammatory Myofibroblastic Tumor
- Gene_Plays_Role_In_Process some Signal Transduction