Terminology Service for NFDI4Health

refractive index detector

Go to external page http://purl.obolibrary.org/obo/OBI_0000583


For analyzing non-UV absorbing substances, such as carbohydrates, lipids and polymers. This is also the detector of choice for gel permeation chromatography. The refractive index detector is one of the least sensitive LC detectors. It is very sensitive to changes in ambient temperature, pressure changes, flow-rate changes and can not be used for gradient elution. Despite these many disadvantages, this detector is extremely useful for detecting those compounds that are nonionic, do not adsorb in the UV, and do not fluoresce. There are many optical systems used in refractive index detectors but one of the most common is the differential refractive index detector.

Term info

Label

refractive index detector

definition source

http://msi-ontology.sourceforge.net/ontology/CHROM.owl#msi_01081, WEB:<http://www.chromatography-online.org/HPLC/Refractive-Index/rs33.html>

editor preferred term

refractive index detector

has curation status

http://purl.obolibrary.org/obo/IAO_0000120

term editor

PERSON:Daniel Schober

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