Terminology Service for NFDI4Health
MeDIP-seq assay
Go to external page
http://purl.obolibrary.org/obo/OBI_0000693
A DNA methylation profiling assay that identifies methylated sites in genomic DNA and determines the methylation pattern that affect gene transcription using immunoprecipitation of methylated genomic DNA, creation of a library of corresponding DNA fragments (either single or paired-end fragments) and subsequent sequencing using parallelized sequencing methods.
Term info
Label
MeDIP-seq assay
alternative term
Methylated DNA immunoprecipitation sequencing assay
definition source
url:https://en.wikipedia.org/wiki/Methylated_DNA_immunoprecipitation
editor preferred term
MeDIP-seq assay
example of usage
PMID: 18612301. A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis. Down TA, Rakyan VK, Turner DJ, Flicek P, Li H, Kulesha E, Gr�_f S, Johnson N, Herrero J, Tomazou EM, Thorne NP, B�_ckdahl L, Herberth M, Howe KL, Jackson DK, Miretti MM, Marioni JC, Birney E, Hubbard TJ, Durbin R, Tavar�� S, Beck S. Nat Biotechnol. 2008 Jul;26(7):779-85.
has curation status
http://purl.obolibrary.org/obo/IAO_0000120
term editor
Philippe Rocca-Serra
Term relations
Subclass of:
- DNA methylation profiling assay
- ChIP assay
- sequencing assay
- has part some sequencing assay
- realizes some (
evaluant role and
role of some (has part some chromatin)) and has_specified_input some (
has part some chromatin and
has role some evaluant role) - has part some library preparation
- has_specified_input some DNA extract
- realizes some (
evaluant role and
role of some DNA extract) and has_specified_input some (
DNA extract and
has role some evaluant role) - has_specified_output some sequence data
- realizes some (
function and
inheres in some DNA sequencer) and has_specified_input some DNA sequencer - has part some chromatin immunoprecipitation
- has_specified_output some (is about some regulation of DNA methylation)
- achieves_planned_objective some epigenetic modification identification objective