Edman degradation
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http://purl.obolibrary.org/obo/OBI_0000705
A sequencing assay in which the amino acid sequence of input peptides or proteins is determined by iteratively cleaving of the amino-terminal (N-terminal) residue without disrupting the peptide bonds and identifying it by e.g. chromatography or electropheresis.
Term info
Label
Edman degradation
definition source
IEDB
editor preferred term
Edman degradation
example of usage
Determination of the amino acid sequence of a peptide eluted from HLA-DRB1*04:01 to be VYPEVTVYPAKT.
has curation status
http://purl.obolibrary.org/obo/IAO_0000120
term editor
IEDB
Term relations
Subclass of:
- sequencing assay
- has_specified_output some (is about some polypeptide)
- realizes some (
molecular label role and
inheres in some material entity) and has_specified_input some material entity - has_specified_output some information content entity