Terminology Service for NFDI4Health
activated partial thromboplastin time assay
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http://purl.obolibrary.org/obo/OBI_0000820
An assay that evaluates blood coagulation by measuring the time required for the appearance of fibrin strands following the mixing blood or plasma with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of blood coaguation . It is used as a screening test and to monitor heparin therapy.
Term info
Label
activated partial thromboplastin time assay
alternative term
aPTT assay
definition source
url:http://www.ebi.ac.uk/ols/ontologies/efo/terms?short_form=EFO_0004310
editor note
There is also the 'partial thromboplastin assay', which some people use synonymously to aPPT, but historically was done slightly differently (without adding a coagulant).
editor preferred term
activated partial thromboplastin time assay
example of usage
The activated partial thromboplastin time (aPTT) was determined using Dade Actin FSL activated PTT reagent (PMID:19696660)
has curation status
http://purl.obolibrary.org/obo/IAO_0000120
term editor
OBI call, Alan Ruttenberg
Term relations
Subclass of:
- assay
- realizes some (
evaluant role and
role of some (blood plasma specimen or blood specimen)) and has_specified_input some (
blood plasma specimen or blood specimen and
has role some evaluant role) - has_specified_output some time measurement datum
- has_specified_output some (is about some blood coagulation)