Terminology Service for NFDI4Health

cell-cell killing assay

Go to external page http://purl.obolibrary.org/obo/OBI_0000882


A cytometry assay that monitors a cell population to track how many are killed by other cells.

Term info

Label

cell-cell killing assay

editor preferred term

cell-cell killing assay

example of usage

Autologous EBV-transformed B-LCL were used as target cells for the influenza virus-specific CTL assays. Equal volumes of target and effector cells were added to tissue culture plates, and 1:2 serial dilutions of effectors were made. After a 4-h incubation of the effector cells with the target cells, supernatants were collected and counted with the LKB 1272 Clinigamma counter. Percent specific killing was determined with the following equation: (experimental 51Cr release - spontaneous 51Cr release)/(maximum 51Cr release - spontaneous 51Cr release) x 100.

has curation status

http://purl.obolibrary.org/obo/IAO_0000120

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