Terminology Service for NFDI4Health
in vitro cell killing assay
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http://purl.obolibrary.org/obo/OBI_0000903
A cell killing assay that measures if and how many target cells are actively killed by other cells in a cell culture.
Term info
Label
in vitro cell killing assay
definition source
IEDB
editor preferred term
in vitro cell killing assay
example of usage
Autologous EBV-transformed B-LCL were used as target cells for the influenza virus-specific CTL assays. Equal volumes of target and effector cells were added to tissue culture plates, and 1:2 serial dilutions of effectors were made. After a 4-h incubation of the effector cells with the target cells, supernatants were collected and counted with the LKB 1272 Clinigamma counter. Percent specific killing was determined with the following equation: (experimental 51Cr release - spontaneous 51Cr release)/(maximum 51Cr release - spontaneous 51Cr release) x 100.
has curation status
http://purl.obolibrary.org/obo/IAO_0000120
term editor
IEDB
Term relations
Equivalent to:
- cell-cell killing assay and realizes some (
evaluant role and
role of some cultured cell population) and has_specified_input some (
cultured cell population and
has role some evaluant role)