binding assay
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http://purl.obolibrary.org/obo/OBI_0001146
An assay with the objective to characterize the disposition of two or more material entities to form a complex.
Term info
Label
binding assay
editor preferred term
binding assay
example of usage
Determination of KD value for an antibody binding a protein using a BIACORE assay. Using plate bound antigen in an ELISA to determine if a mixture of serum antibodies bind the antigen. The following are NOT binding assays, as the desired output is not binding data: RNA microarray experiments to determine levels of gene expression. ChIP experiments to determine where in DNA a transcription factor binds. Using an IL-2 antibody on an ELISA plate to determine presence of IL-2 after stimulating a T cell culture.
has curation status
http://purl.obolibrary.org/obo/IAO_0000123
term editor
Randi Vita, Jason Greenbaum, Bjoern Peters
Term relations
Subclass of:
- assay
- has_specified_output some binding datum
- has_specified_output some (is about some binding)