Terminology Service for NFDI4Health

binding assay

Go to external page http://purl.obolibrary.org/obo/OBI_0001146


An assay with the objective to characterize the disposition of two or more material entities to form a complex.

Term info

Label

binding assay

editor preferred term

binding assay

example of usage

Determination of KD value for an antibody binding a protein using a BIACORE assay. Using plate bound antigen in an ELISA to determine if a mixture of serum antibodies bind the antigen. The following are NOT binding assays, as the desired output is not binding data: RNA microarray experiments to determine levels of gene expression. ChIP experiments to determine where in DNA a transcription factor binds. Using an IL-2 antibody on an ELISA plate to determine presence of IL-2 after stimulating a T cell culture.

has curation status

http://purl.obolibrary.org/obo/IAO_0000123

term editor

Randi Vita, Jason Greenbaum, Bjoern Peters

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