Terminology Service for NFDI4Health

half maximal effective concentration (EC50)

Go to external page http://purl.obolibrary.org/obo/OBI_0001180


half maximal effective concentration (EC50) is a scalar measurement datum corresponding to the concentration of a compound which induces a response halfway between the baseline and maximum after some specified exposure time.

Term info

Label

half maximal effective concentration (EC50)

definition source

wikipedia

editor preferred term

half maximal effective concentration (EC50)

example of usage

Determining the potentency of a drug / antibody / toxicant by measuring a graded dose response curve, and determining the concentration of the compound where 50% of its maximal effect is observed.

has curation status

http://purl.obolibrary.org/obo/IAO_0000120

term editor

Bjoern Peters; Randi Vita