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half maximal inhibitory concentration (IC50)

Go to external page http://purl.obolibrary.org/obo/OBI_0001191


Half maximal inhibitory concentration (IC50) is a scalar measurement datum that measures the effectiveness of a compound to competitively inhibit a given process, and corresponds to the concentration of the compound at which it reaches half of its maximum inhibitory effect.

Term info

Label

half maximal inhibitory concentration (IC50)

definition source

wikipedia

editor preferred term

half maximal inhibitory concentration (IC50)

example of usage

Interpolating that at a dose of IC50=12 nM, half of the binding of a comptetitive ligand is inhibited.

has curation status

http://purl.obolibrary.org/obo/IAO_0000120

term editor

Bjoern Peters; Randi Vita