Terminology Service for NFDI4Health
Sos-recruitment assay
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http://purl.obolibrary.org/obo/OBI_0001680
A binding assay that detects interacting proteins for a targeted domain where mammalian guanyl nucleotide exchange factor (GEF) Sos is recruited to the Saccharomyces cerevisiae plasma membrane harboring a temperature-sensitive Ras GEF, Cdc25-2, allowing growth at the nonpermissive temperature using the Sos recruitment system, a kind of yeast 2 hybrid system.
Term info
Label
Sos-recruitment assay
alternative term
SRS
definition source
PMID:9154808
editor preferred term
Sos-recruitment assay
example of usage
The Sos-recruitment system as a tool to analyze cellular localization of plant proteins: membrane localization of Arabidopsis thaliana PEPINO/PASTICCINO2. PMID:20300944
has curation status
http://purl.obolibrary.org/obo/IAO_0000122
term editor
Marcus Chibucos, Philippe Rocca-Serra