Terminology Service for NFDI4Health
methylation-specific polymerase chain reaction assay
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http://purl.obolibrary.org/obo/OBI_0001684
An assay that uses initial modification of DNA by sodium bisulfite, converting all unmethylated, but not methylated, cytosines to uracil, and subsequent amplification with primers specific for methylated versus unmethylated DNA.
Term info
Label
methylation-specific polymerase chain reaction assay
alternative term
MSP
definition source
PMID:8790415
editor preferred term
methylation-specific polymerase chain reaction assay
example of usage
Methylation status of breast cancer resistance protein detected by methylation-specific polymerase chain reaction analysis is correlated inversely with its expression in drug-resistant lung cancer cells. PMID:18219662
has curation status
http://purl.obolibrary.org/obo/IAO_0000122
term editor
Marcus Chibucos, Philippe Rocca-Serra
Term relations
Subclass of:
- assay
- has_specified_output some (is about some regulation of DNA methylation)
- has_specified_output some data item