Terminology Service for NFDI4Health
amplification of intermethylated sites assay
Go to external page
http://purl.obolibrary.org/obo/OBI_0001685
An assay that estimates genome-wide DNA methylation and measures methylation of DNA sequences. AIMS is based on the differential enzymatic digestion of genomic DNA with methylation-sensitive and methylation-insensitive isoschizomers followed by restrained PCR amplification of methylated sequences.
Term info
Label
amplification of intermethylated sites assay
alternative term
intermethylated site amplification, AIMS assay
definition source
PMID:18987810
editor preferred term
amplification of intermethylated sites assay
example of usage
Analysis of DNA methylation by amplification of intermethylated sites (AIMS). PMID:18987810
has curation status
http://purl.obolibrary.org/obo/IAO_0000122
term editor
Marcus Chibucos, Philippe Rocca-Serra