DNase I hypersensitive sites sequencing assay
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http://purl.obolibrary.org/obo/OBI_0001853
An assay that identifies the location of regulatory regions, based on the genome-wide sequencing of regions super sensitive to cleavage by DNase I.
Term info
Label
DNase I hypersensitive sites sequencing assay
definition source
url:http://en.wikipedia.org/wiki/DNase-Seq
editor preferred term
DNase I hypersensitive sites sequencing assay
example of usage
Sabo, et al. Discovery of functional noncoding elements by digital analysis of chromatin structure. Proc Natl Acad Sci U S A. 2004 Nov 30;101(48):16837-42. [PMID:15550541]
has curation status
http://purl.obolibrary.org/obo/IAO_0000120
term editor
Venkat Malladi, Chris Stoeckert, Jie Zheng
Term relations
Subclass of:
- DNA sequencing assay
- achieves_planned_objective some protein and DNA interaction identification objective
- has part some library preparation
- has part some DNA sequencing assay
- has part some non specific enzymatic cleavage
- has_specified_output some DNA sequence data
- realizes some (
evaluant role and
role of some DNA extract) and has_specified_input some (
DNA extract and
has role some evaluant role) - realizes some (
function and
inheres in some DNA sequencer) and has_specified_input some DNA sequencer