Terminology Service for NFDI4Health
methylation-sensitive restriction enzyme sequencing assay
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http://purl.obolibrary.org/obo/OBI_0001861
An assay that identifies unmethylated CpGs using methylation sensitive restriction enzymes to fragment DNA.
Term info
Label
methylation-sensitive restriction enzyme sequencing assay
alternative term
MRE-seq assay, MRE-seq
definition source
PMID:20613842
editor preferred term
methylation-sensitive restriction enzyme sequencing assay
example of usage
Maunakea et al. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature. 2010 Jul 8;466(7303):253-7. [PMID:20613842]
has curation status
http://purl.obolibrary.org/obo/IAO_0000120
term editor
Venkat Malladi, Chris Stoeckert, Jie Zheng
Term relations
Subclass of:
- DNA sequencing assay
- DNA methylation profiling by high throughput sequencing assay
- has part some library preparation
- has part some DNA sequencing assay
- has_specified_output some DNA sequence data
- realizes some (
evaluant role and
role of some DNA extract) and has_specified_input some (
DNA extract and
has role some evaluant role) - realizes some (
function and
inheres in some DNA sequencer) and has_specified_input some DNA sequencer - has_specified_output some (is about some regulation of DNA methylation)
- achieves_planned_objective some epigenetic modification identification objective
- has part some specific enzymatic cleavage