micrococcal nuclease digestion followed by high throughput sequencing assay
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http://purl.obolibrary.org/obo/OBI_0001924
An assay that identifies nucleosome positioning by genome wide sequencing of regions sensitive to digestion by micrococal nuclease
Term info
Label
micrococcal nuclease digestion followed by high throughput sequencing assay
alternative term
MNase-seq, MNase-seq assay
definition source
PMID:17038564
editor preferred term
micrococcal nuclease digestion followed by high throughput sequencing assay
example of usage
Cui et al.Genome-wide approaches to determining nucleosome occupancy in metazoans using MNase-Seq. Methods Mol Biol. 2012;833:413-9. [PMID:22183607]
has curation status
http://purl.obolibrary.org/obo/IAO_0000120
term editor
Venkat Malladi, Chris Stoeckert, Jie Zheng
Term relations
Subclass of:
- DNA sequencing assay
- achieves_planned_objective some protein and DNA interaction identification objective
- has part some library preparation
- has part some non specific enzymatic cleavage
- has_specified_output some DNA sequence data
- realizes some (
evaluant role and
role of some DNA extract) and has_specified_input some (
DNA extract and
has role some evaluant role) - realizes some (
function and
inheres in some DNA sequencer) and has_specified_input some DNA sequencer