Terminology Service for NFDI4Health
genome coverage
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http://purl.obolibrary.org/obo/OBI_0001939
A data item that is the total number of bases in reads, divided by genome size, assumed to be the reference size (for instance of 3.10 Gb for human and 2.73 Gb for mouse) and refers to the percentage of the genome that is contained in the assembly based on size estimates; these are usually based on cytological techniques. Genome coverage of 90–95% is generally considered to be good, as most genomes contain a considerable fraction of repetitive regions that are difficult to sequence. So it is not a cause for concern if the genome coverage of an assembly is a bit less than 100%.
Term info
Label
genome coverage
definition source
A beginner's guide to eukaryotic genome annotation. Yandell M, Ence D. Nat Rev Genet. 2012 Apr 18;13(5):329-42. doi: 10.1038/nrg3174. PMID: 22510764
editor preferred term
genome coverage
example of usage
Gigascience. 2012 Dec 27;1(1):18. doi: 10.1186/2047-217X-1-18. PMID: 23587118. "The genome coverage increased from 81.16% to 93.91%"
has curation status
http://purl.obolibrary.org/obo/IAO_0000122
term editor
Alejandra Gonzalez-Beltran, Philippe Rocca-Serra
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