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chromosome conformation capture-on-chip assay

Go to external page http://purl.obolibrary.org/obo/OBI_0002458

A nuclear ligation assay which uses cross-linking of proteins to proteins and DNA, followed by two rounds of digestion and ligation, inverse PCR, and characterization by microarray or DNA sequencing. This enables unbiased genome-wide screens for DNA contacts made by single genomic sites of interest.

Term info

Label

chromosome conformation capture-on-chip assay

alternative term

circularized chromosome conformation capture assay, 4C assay

definition source

url:http://www.sciencedirect.com/science/article/pii/B9780123919380000045

editor preferred term

chromosome conformation capture-on-chip assay

has curation status

http://purl.obolibrary.org/obo/IAO_0000120

term editor

Rebecca Jackson

term tracker item

https://github.com/obi-ontology/obi/issues/875