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RNAi knockdown assay

http://purl.obolibrary.org/obo/OBI_0002628

A gene knockdown assay in which RNAi gene knockdown is used to disrupt gene transcripts.

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Term info

Label

RNAi knockdown assay

alternative term

RNAi gene knockdown assay, RNA interference knockdown assay

definition source

Rebecca Jackson

editor preferred term

RNAi knockdown assay

example of usage

"Here, we described the development of RNAi by micro-injection of double-stranded RNA (dsRNA) in the pea aphid Acyrthosiphon pisum. Injection of dsRNA into whole aphid body induced the silencing of two marker genes with different expression patterns: the ubiquitously expressed Ap-crt genes encoding a calreticulin and the gut specific Ap-cath-L gene encoding a cathepsin-L." (PMID:17903251)

has curation status

http://purl.obolibrary.org/obo/IAO_0000125

term editor

Rebecca Jackson

term tracker item

https://github.com/obi-ontology/obi/issues/1057

Term relations

Subclass of:

gene knock-down assay
has part some RNAi gene knockdown