Terminology Service for NFDI4Health
comet assay
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http://purl.obolibrary.org/obo/OBI_0302736
An assay that measures DNA damage (DNA breakage) in eucaryotic cells exposed to a challenge by determining the size and shape of DNA migration by detecting fluorescently labeled DNA from a cell placed in an electric field using gel electrophoresis
Term info
Label
comet assay
alternative term
SCGE assay, single cell gel electrophoresis assay
definition source
PMID:7686265
editor preferred term
comet assay
example of usage
PMID: 18326531.Mutagenesis. 2008 Mar 6.Recommendations for design of the rat comet assay.
has curation status
http://purl.obolibrary.org/obo/IAO_0000122
term editor
Philippe Rocca-Serra
Term relations
Subclass of:
- cytometry assay
- realizes some (
reagent role and
inheres in some (
material entity and
bearer of some fluorescence and
has role some dye role)) and has_specified_input some (
material entity and
bearer of some fluorescence and
has role some dye role) - has part some fluorescence microscopy
- has_specified_output some (is about some cellular response to DNA damage stimulus)
- realizes some (
evaluant role and
role of some cell) and has_specified_input some (
cell and
has role some evaluant role) - has_specified_input some agarose gel
- has_specified_output some information content entity