Terminology Service for NFDI4Health
cell bound MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using fluorescence detection
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http://purl.obolibrary.org/obo/OBI_0001520
A cell bound MHC ligand binding half maximal inhibitory concentration (IC50) determination assay that uses fluorescence detection to detect loss of binding of a known reference ligand due to competition by the ligand under investigation.
Term info
Label
cell bound MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using fluorescence detection
IEDB alternative term
half maximal inhibitory concentration (IC50)|cellular MHC/competitive/fluorescence|nM
definition source
IEDB
editor preferred term
cell bound MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using fluorescence detection
has curation status
http://purl.obolibrary.org/obo/IAO_0000120
term editor
PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters
Term relations
Equivalent to:
- assay measuring the half maximal inhibitory concentration [IC50] of a MHC:ligand complex and has part some fluorescence detection assay and has_specified_input some (
material entity and
has role some competitive binding reference ligand role) and has_specified_input some (
cell and
has part some MHC protein complex) and has_specified_output some (has measurement unit label value nanomolar)