Terminology Service for NFDI4Health
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cranial nerve II

Go to external page http://purl.obolibrary.org/obo/UBERON_0000941

Cranial nerve fiber tract which is comprised of retinal ganglion cell axons running posterior medially towards the optic chiasm, at which some of the axons cross the midline and after which the structure is termed the optic tract. Transmits visual information from the retina to the brain[ZFA]. [ https://www.worldcat.org/search?q=bn%3A0471888893 https://www.worldcat.org/search?q=bn%3A0471209627 ]

Term info

Label

cranial nerve II

Synonyms
  • 02 optic nerve
  • cranial II
  • nervus opticus
  • nervus opticus [II]
  • optic II
  • optic II nerve
  • optic nerve [II]
  • second cranial nerve
database cross reference
Subsets

uberon_slim, efo_slim, pheno_slim, vertebrate_core

abbreviation
2n [ BIRNLEX : 1640 NIFSTD : NeuroNames_abbrevSource ]

latin term
nervus opticus [II] [ FMA : 50863 FMA : TA ]

taxonomic disambiguation
optic nerve [ FMA : 50863 ZFA : 0000435 ]

latin term
nervus opticus

editor note

Do not classify under 'cranial nerve', as this is not a true nerve - should be classified as evaginated sensory afferent[ISBN:0471888893]

external definition

A collection of nerve cells that project visual information from the eyes to the brain. (Source: BioGlossary, www.Biology-Text.com)[TAO], Fibrous, somatic sensory element covered by a fibrous connective-tissue sheath and is continuous with the layer of nerve cells on the inner surface of the eye.[AAO]

external ontology notes

(relaion to eye): MA, XAO, AAO and BTO consider this part of the eye. This is in contrast to GO, FMA, EHDAA2 (FMA has a class 'intra-ocular part of optic nerve' which represents the region of overlap). Relation to brain: part of diencephalon in EHDAA2, ZFA. In NIF, has the optic nerve root as part, which is a feature part of the diencphalon

has broad synonym

2n, optic nerve

has related synonym

CN-II, nerve II, optic

homology notes

(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup (reference 1); The (optic) stalk persists as the optic nerve (reference 2).[well established][VHOG]

id

UBERON:0000941