Terminology Service for NFDI4Health
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skin epidermis

Go to external page http://purl.obolibrary.org/obo/UBERON_0001003

The outer epithelial layer of the skin that is superficial to the dermis. [ http://orcid.org/0000-0002-6601-2165 https://www.worldcat.org/search?q=bn%3A0073040584 ]

Term info

Label

skin epidermis

Synonyms
  • vertebrate epidermis
database cross reference
Subsets

uberon_slim, efo_slim, pheno_slim, vertebrate_core

axiom lost from external ontology

relationship loss: subclass external integument structures (AAO:0000961)[AAO]

external definition

The outer epithelial layer of the external integument of the body that is derived from the embryonic epiblast.[AAO], A cellular, multilayered epithelium derived from the ectoderm. Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. Le Guellec et al, 2004.[TAO]

has broad synonym

skin, epidermis

homology notes

(...) outer epithelia in all metazoan animals are homologous. (...) The ancestor of all metazoans likely had an epidermis with a basal extracellular matrix (ECM), an apical extracellular glycocalyx, and one cilium with a striated rootlet per cell.[well established][VHOG]

id

UBERON:0001003

taxon notes

Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. In terrestrial vertebrates the epidermis often forms an outer keratinized or cornified layer, the stratum corneum. Interaction between the epideris and dermis gives rise to feathers (birds), hair and mammary glands (mammals), teeth and scales (placoid: chondrichthyans; cosmoids, ganoid, cycloid in bony fishes).