http://purl.obolibrary.org/obo/Illu_spleen.jpg

An organ involved in red blood cell filtration and immune response.[AAO]

It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells

uberon

lien

lienal, splenic

With the advent of clonal selection, the accumulation and segregation of T and B cells in specialized organs for antigen presentation became necessary, and indeed the spleen is found in all jawed vertebrates, but not in agnathans or invertebrates.[well established][VHOG]

UBERON:0002106

In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron, Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96)

• red pulp of spleen
• spleen capsule
• spleen perifollicular zone
• spleen trabecular artery
• spleen trabecular vein
• white pulp of spleen

• celiac artery

• gastro-splenic ligament

• splenic artery

• lieno-renal ligament

• parenchyma of spleen
• marginal zone of spleen
• hilum of spleen
• spleen capsule
• spleen smooth muscle
• spleen perifollicular zone
• Schweigger-Seidel sheath
• splenic arteriole
• vasculature of spleen