Terminology Service for NFDI4Health

roof plate

Go to external page http://purl.obolibrary.org/obo/UBERON_0003054


A single row of glia at the dorsal midline of the developing neural tube along the entire anterior-posterior axis. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells. [ http://amigo.geneontology.org/amigo/term/GO:0021509 http://www.ncbi.nlm.nih.gov/pubmed/15378040 ]

Term info

Label

roof plate

Synonyms
  • roof plate neural tube
  • roof plate neural tube region
  • roofplate
database cross reference
Subsets

uberon_slim, pheno_slim, vertebrate_core

editor note

TODO - Note that although this is classically defined as being located on the neural tube, in many AOs the roof plate continues post-embryonically after the neural tube has ceased to exist. Consider 'roof plate of neural tube'. TODO - alar plate vs roof plate

external definition

Multi-tissue structure that is the dorsal-most aspect of the devleloping neural tube.[TAO]

has alternative id

UBERON:0003298

has related synonym

alar plate, future brain roof plate

id

UBERON:0003054