sclerotome
Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. [ http://en.wikipedia.org/wiki/Sclerotome https://github.com/obophenotype/uberon/issues/316 ]
Term info
sclerotome
- sclerotomes
uberon_slim, pheno_slim, vertebrate_core
http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png
Skeletogenic portion of somites.[AAO]
part_of somite in XAO
uberon
sclerotomus
The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG]
UBERON:0003089