Terminology Service for NFDI4Health
ultimobranchial body
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http://purl.obolibrary.org/obo/UBERON_0003092
An outpocketing of one of the caudal pharyngeal pouches that is comprised on calcitonin-producing parafollicular cells. [ http://en.wikipedia.org/wiki/Ultimopharyngeal_body https://www.worldcat.org/search?q=bn%3A0073040584 ]
Term info
Label
ultimobranchial body
Synonyms
- corpus ultimopharyngeum
- ultimobranchial gland
- ultimopharyngeal body
- ultimopharyngeal gland
Subsets
uberon_slim, pheno_slim, vertebrate_core
editor note
TODO - ensure developmental relationships correct across species. WP says pouch 4, but this isn't supported by Kardong (table 13.1 or fig 15.5). MP says 'fifth pouch in human or as the ventral component of the fourth pouch in mouse'. EHDAA2 says 6th arch mesenchyme http://www.ncbi.nlm.nih.gov/pubmed/16313389 says: the most posterior pouch generates the ultimobranchial bodies in most vertebrate classes, but mammals do not contain this structure
external definition
Anatomical structure which includes small, calcitonin producing glands originating as epithelial growths from the sixth pharyngeal pouch.[AAO], The glandular tissue originating from the fifth branchial pouch which combines with the buccal cavity outgrowth to form the thyroid and contributes calcitonin-secreting cells to the gland. [TFD][VHOG]
has obo namespace
uberon
has related synonym
telopharyngeal body, ultimobranchial bodies, postbranchial body, telobranchial body, ultimobranchial
homology notes
(...) ultimobranchial bodies that develop in all vertebrates from the ventral or posterior surface of the last pair of pharyngeal pouches. The ultimobranchial bodies are vestigial in most mammals (...).[well established][VHOG]
id
UBERON:0003092
taxon notes
The ultimobranchial bodies of lower vertebrates contain large amounts of calcitonin. In mammals the bodies fuse with the thyroid gland and are thought to develop into the parafollicular cells. (Stedman, 25th ed), In humans, the ultimobranchial body is an embryological structure that gives rise to the calcitonin-producing cells - also called parafollicular cells or clear cells - of the thyroid gland. In humans, this body is a derivative of the ventral recess of the fourth pharyngeal pouch (or fifth)