Terminology Service for NFDI4Health
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Rathke's pouch

Go to external page http://purl.obolibrary.org/obo/UBERON_0005356

A pouch of ectoderm that grows out from the upper surface of the embryonic stomodeum and gives rise to the anterior and intermediate lobes of the pituitary gland[MP]. In embryogenesis, Rathke's pouch is a depression in the roof of the developing mouth in front of the buccopharyngeal membrane. It gives rise to the anterior pituitary (adenohypophysis), a part of the endocrine system[WP]. [ http://en.wikipedia.org/wiki/Rathke's_pouch ]

Term info

Label

Rathke's pouch

Synonyms
  • Rathke pouch
  • pouch of Rathke
database cross reference
Subsets

pheno_slim

dubious for taxon

http://purl.obolibrary.org/obo/NCBITaxon_7955

external definition

A depression that forms in the roof of the mouth of an embryo, anterior to the buccopharyngeal membrane. The walls of the diverticulum develop into the anterior lobe of the pituitary gland. [TFD][VHOG]

external ontology notes

EHDAA2 distinguishes between the adenohypophyseal pouch and it's precursor Rathke's pouch epithelium.

has narrow synonym

adenohypophysial pouch, Rathkes pouch epithelium

has related synonym

craniopharyngeal pouch, hypophyseal pouch, Rathke's cleft, pituitary diverticulum, hypophyseal diverticulum, Rathke's pocket, nasohypophyseal pouch, craniobuccal pouch, Rathke's cyst

homology notes

It (the hypophysis) develops embryonically in all vertebrates from two ectodermal evaginations that meet and unite. An infundibulum grows ventrally from the diencephalon of the brain, and Rathke's pouch extends dorsally from the roof of the developing mouth, or stomodaeum. The infundibulum remains connected to the floor of the diencephalon, which becomes the hypothalamus, and gives rise to the part of the gland known as the neurohypophysis. (...) Rathke's pouch loses its connection with the stomodaeum in most adult vertebrates and gives rise to the rest of the gland, the adenohypophysis. (...) A well-developed hypophyseal system with functional connections to the hypothalamus is unique to craniates.[well established][VHOG]

id

UBERON:0005356

taxon notes

median funnel­-shaped invagination of ectoderm, the nasohypophyseal pouch. It will contribute to the formation of the pituitary gland of the adult lamprey and is homologous to Rathke's pouch and perhaps to Hatschek 's pit (amphioxus).