Terminology Service for NFDI4Health

base of crypt of Lieberkuhn

Go to external page http://purl.obolibrary.org/obo/UBERON_0013739


The basal portion (further from lumen) of an intestinal crypt. Contains multipotent stem cells. Stem cells in the crypts divide to form daughter cells. One daughter cell from each stem cell division is retained as a stem cell. The other becomes committed to differentiate along one of four pathways to become an enterocyte, enteroendocrine cell, goblet cell or Paneth cell. [ http://purl.obolibrary.org/obo/UBERON_md http://orcid.org/0000-0002-6601-2165 ]

Term info

Label

base of crypt of Lieberkuhn

Synonyms
  • basal portion of intestinal gland
  • base of intestinal gland
  • base part of epithelium of intestinal gland
id

UBERON:0013739

taxon notes

Clearly defined prolifieration zones found in mammals. Not observed in agnathostomes, larval amphibians. Described in advanced species of fish and adult amphibians.