Terminology Service < Semantic Lookup Platform

Tumor necrosis factor receptor superfamily member 6

https://identifiers.org/uniprot:P25446

Function: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity).

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Term info

Label

Tumor necrosis factor receptor superfamily member 6

Synonyms

Tumor necrosis factor receptor superfamily member 6

database cross reference

exactMatch

https://identifiers.org/uniprotTNR6_MOUSE, https://identifiers.org/uniprotQ6GT31

inScheme

https://identifiers.org/uniprot

prefLabel

Tumor necrosis factor receptor superfamily member 6

Term relations

Subclass of:

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