Terminology Service < Semantic Lookup Platform

Centromere protein C

https://identifiers.org/uniprot:P49452

Function: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.

Tree view

Term info

Label

Centromere protein C

Synonyms

Centromere protein C

database cross reference

exactMatch

https://identifiers.org/uniprotCENPC_MOUSE

inScheme

https://identifiers.org/uniprot

prefLabel

Centromere protein C

Term relations

Subclass of:

Thing