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Interleukin-10 receptor subunit beta

https://identifiers.org/uniprot:Q08334

Function: Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.

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Term info

Label

Interleukin-10 receptor subunit beta

Synonyms

Interleukin-10 receptor subunit beta

database cross reference

exactMatch

https://identifiers.org/uniprotI10R2_HUMAN

inScheme

https://identifiers.org/uniprot

prefLabel

Interleukin-10 receptor subunit beta

Term relations

Subclass of:

Thing