Terminology Service for NFDI4Health

Sodium-dependent phosphate transporter 2

Go to external page https://identifiers.org/uniprot:Q08357


Function: Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not significantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants.

Term info

Label

Sodium-dependent phosphate transporter 2

Synonyms
  • Sodium-dependent phosphate transporter 2
database cross reference
exactMatch

https://identifiers.org/uniprotS20A2_HUMAN

inScheme

https://identifiers.org/uniprot

prefLabel

Sodium-dependent phosphate transporter 2

Term relations

Subclass of: