Terminology Service for NFDI4Health

Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

Go to external page https://identifiers.org/uniprot:Q32PX2


Function: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Term info

Label

Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

Synonyms
  • Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
database cross reference
exactMatch

https://identifiers.org/uniprotAIMP2_RAT

inScheme

https://identifiers.org/uniprot

prefLabel

Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

Term relations

Subclass of: