Terminology Service for NFDI4Health

Small RNA 2'-O-methyltransferase

Go to external page https://identifiers.org/uniprot:Q32PY6


Function: Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.

Term info

Label

Small RNA 2'-O-methyltransferase

Synonyms
  • Small RNA 2'-O-methyltransferase
database cross reference
exactMatch

https://identifiers.org/uniprotHENMT_RAT

inScheme

https://identifiers.org/uniprot

prefLabel

Small RNA 2'-O-methyltransferase

Term relations

Subclass of: