Terminology Service < Semantic Lookup Platform

Interleukin-17 receptor A

https://identifiers.org/uniprot:Q60943

Function: Receptor for IL17A (PubMed:17911633, PubMed:20554964, PubMed:8777726). Receptor for IL17F (PubMed:17911633, PubMed:20554964). Binds to IL17A with higher affinity than to IL17F (PubMed:17911633). Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC (By similarity). Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC (By similarity). Receptor for IL17C as part of a heterodimeric complex with IL17RE (PubMed:21993848, PubMed:21993849, PubMed:21982598). Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6 (By similarity).

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Term info

Label

Interleukin-17 receptor A

Synonyms

Interleukin-17 receptor A

database cross reference

exactMatch

https://identifiers.org/uniprotI17RA_MOUSE

inScheme

https://identifiers.org/uniprot

prefLabel

Interleukin-17 receptor A

Term relations

Subclass of:

Thing