Terminology Service < Semantic Lookup Platform

Serine/threonine/tyrosine-interacting protein

https://identifiers.org/uniprot:Q60969

Function: Catalytically inactive phosphatase (PubMed:7592916). Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2) (By similarity). Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2) (By similarity). By binding to the F-box of FBXW7, prevents the assembly of FBXW7 into the SCF E3 ubiquitin-protein ligase complex, and thereby inhibits degradation of its substrates (By similarity). Plays a role in spermatogenesis (PubMed:11842224).

Tree view

Term info

Label

Serine/threonine/tyrosine-interacting protein

Synonyms

Serine/threonine/tyrosine-interacting protein

database cross reference

exactMatch

https://identifiers.org/uniprotSTYX_MOUSE, https://identifiers.org/uniprotQ60970, https://identifiers.org/uniprotQ3TMA3

inScheme

https://identifiers.org/uniprot

prefLabel

Serine/threonine/tyrosine-interacting protein

Term relations

Subclass of:

Thing