Terminology Service < Semantic Lookup Platform

RAS guanyl-releasing protein 2

https://identifiers.org/uniprot:Q7LDG7

Function: Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.

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Term info

Label

RAS guanyl-releasing protein 2

Synonyms

RAS guanyl-releasing protein 2

database cross reference

exactMatch

https://identifiers.org/uniprotA6NDC7, https://identifiers.org/uniprotGRP2_HUMAN, https://identifiers.org/uniprotO00538

inScheme

https://identifiers.org/uniprot

prefLabel

RAS guanyl-releasing protein 2

Term relations

Subclass of:

Thing