Cytosolic carboxypeptidase 3
Go to external page
https://identifiers.org/uniprot:Q8CDP0
Function: Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin.
Term info
Label
Cytosolic carboxypeptidase 3
Synonyms
- Cytosolic carboxypeptidase 3
database cross reference
- EC:3.4.17.-
- EMBL:AK029793
- EMBL:AK030378
- EMBL:BC028521
- EMBL:BC087897
- EMBL:BC139065
- EMBL:DQ867031
- EMBL:DQ867032
- GO:0004181
- GO:0005829
- GO:0008270
- GO:0035610
- InterPro:IPR000834
- InterPro:IPR040626
- iPTMnet:Q8CDP0
- MGI:1923473
- Pfam:PF00246
- Pfam:PF18027
- RefSeq:NP_001276585.1
- RefSeq:NP_001276586.1
- RefSeq:NP_001276587.1
- RefSeq:NP_848745.2
- Bgee:ENSMUSG00000038836
- CCDS:CCDS19995.2
- CCDS:CCDS80515.1
- CCDS:CCDS80516.1
- CTD:340351
- eggNOG:COG2866
- eggNOG:KOG1814
- eggNOG:KOG3641
- Ensembl:ENSMUST00000115014
- Ensembl:ENSMUST00000115016
- Ensembl:ENSMUST00000115017
- ExpressionAtlas:Q8CDP0
- GeneID:76223
- GeneTree:ENSGT00940000160916
- Genevisible:Q8CDP0
- HOGENOM:HOG000111052
- InParanoid:Q8CDP0
- KEGG:mmu:76223
- KO:K23437
- OMA:NCDNTLM
- OrthoDB:481670at2759
- PaxDb:Q8CDP0
- PhosphoSitePlus:Q8CDP0
- PhylomeDB:Q8CDP0
- PRIDE:Q8CDP0
- PRO:PR:Q8CDP0
- Proteomes:UP000000589
- RNAct:Q8CDP0
- STRING:10090.ENSMUSP00000110669
- TreeFam:TF313794
- UCSC:uc009bhm.2
- UCSC:uc009bhp.1
- UCSC:uc009bhq.1
- UCSC:uc009bhr.2
- UCSC:uc009bhs.2
exactMatch
https://identifiers.org/uniprotQ8BSW4, https://identifiers.org/uniprotQ09M07, https://identifiers.org/uniprotQ09M06, https://identifiers.org/uniprotCBPC3_MOUSE, https://identifiers.org/uniprotB2RSY8
inScheme
https://identifiers.org/uniprot
prefLabel
Cytosolic carboxypeptidase 3