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WD repeat and FYVE domain-containing protein 1

https://identifiers.org/uniprot:Q8IWB7

Function: Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines (PubMed:25736436).

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Term info

Label

WD repeat and FYVE domain-containing protein 1

Synonyms

WD repeat and FYVE domain-containing protein 1

database cross reference

exactMatch

https://identifiers.org/uniprotQ53S17, https://identifiers.org/uniprotWDFY1_HUMAN, https://identifiers.org/uniprotQ9H9D5

inScheme

https://identifiers.org/uniprot

prefLabel

WD repeat and FYVE domain-containing protein 1

Term relations

Subclass of:

Thing