Terminology Service < Semantic Lookup Platform

MAX gene-associated protein

https://identifiers.org/uniprot:Q8IWI9

Function: Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor (By similarity).

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Term info

Label

MAX gene-associated protein

Synonyms

MAX gene-associated protein

database cross reference

exactMatch

https://identifiers.org/uniprotF5H7K2, https://identifiers.org/uniprotQ9UG69, https://identifiers.org/uniprotQ9H9N7, https://identifiers.org/uniprotB9EGR5, https://identifiers.org/uniprotMGAP_HUMAN, https://identifiers.org/uniprotE7ENI0, https://identifiers.org/uniprotQ9H8R3

inScheme

https://identifiers.org/uniprot

prefLabel

MAX gene-associated protein

Term relations

Subclass of:

Thing