Terminology Service for NFDI4Health

Protein KIBRA

Go to external page https://identifiers.org/uniprot:Q8IX03


Function: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.

Term info

Label

Protein KIBRA

Synonyms
  • Protein KIBRA
database cross reference
exactMatch

https://identifiers.org/uniprotO94946, https://identifiers.org/uniprotQ8WVM4, https://identifiers.org/uniprotQ6MZX4, https://identifiers.org/uniprotQ7Z4G8, https://identifiers.org/uniprotQ6Y2F8, https://identifiers.org/uniprotKIBRA_HUMAN, https://identifiers.org/uniprotB4DK05

inScheme

https://identifiers.org/uniprot

prefLabel

Protein KIBRA

Term relations

Subclass of: