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Cytosolic carboxypeptidase-like protein 5

https://identifiers.org/uniprot:Q8NDL9

Function: Metallocarboxypeptidase that mediates protein deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/CCP1, AGBL2/CCP2, AGBL3/CCP3, AGBL1/CCP4 and AGBL4/CCP6. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS.

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Term info

Label

Cytosolic carboxypeptidase-like protein 5

Synonyms

Cytosolic carboxypeptidase-like protein 5

database cross reference

exactMatch

https://identifiers.org/uniprotCBPC5_HUMAN, https://identifiers.org/uniprotQ96IK8, https://identifiers.org/uniprotA2VDI7, https://identifiers.org/uniprotQ9H6V0, https://identifiers.org/uniprotB7WPG9, https://identifiers.org/uniprotD6W548, https://identifiers.org/uniprotQ53SZ0, https://identifiers.org/uniprotB7Z7I7, https://identifiers.org/uniprotQ53SW0

inScheme

https://identifiers.org/uniprot

prefLabel

Cytosolic carboxypeptidase-like protein 5

Term relations

Subclass of:

Thing