Terminology Service for NFDI4Health

Trinucleotide repeat-containing gene 6A protein

Go to external page https://identifiers.org/uniprot:Q8NDV7


Function: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As a scaffolding protein, associates with argonaute proteins bound to partially complementary mRNAs, and can simultaneously recruit CCR4-NOT and PAN deadenylase complexes.

Term info

Label

Trinucleotide repeat-containing gene 6A protein

Synonyms
  • Trinucleotide repeat-containing gene 6A protein
database cross reference
exactMatch

https://identifiers.org/uniprotQ658L5, https://identifiers.org/uniprotTNR6A_HUMAN, https://identifiers.org/uniprotQ8TBT8, https://identifiers.org/uniprotC9JAR8, https://identifiers.org/uniprotQ8TCR0, https://identifiers.org/uniprotO15408, https://identifiers.org/uniprotQ6NVB5, https://identifiers.org/uniprotQ8NEZ0, https://identifiers.org/uniprotQ9NV59

inScheme

https://identifiers.org/uniprot

prefLabel

Trinucleotide repeat-containing gene 6A protein

Term relations

Subclass of: