Trinucleotide repeat-containing gene 6A protein
Function: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As a scaffolding protein, associates with argonaute proteins bound to partially complementary mRNAs, and can simultaneously recruit CCR4-NOT and PAN deadenylase complexes.
Term info
Trinucleotide repeat-containing gene 6A protein
- Trinucleotide repeat-containing gene 6A protein
https://identifiers.org/uniprotQ658L5, https://identifiers.org/uniprotTNR6A_HUMAN, https://identifiers.org/uniprotQ8TBT8, https://identifiers.org/uniprotC9JAR8, https://identifiers.org/uniprotQ8TCR0, https://identifiers.org/uniprotO15408, https://identifiers.org/uniprotQ6NVB5, https://identifiers.org/uniprotQ8NEZ0, https://identifiers.org/uniprotQ9NV59
https://identifiers.org/uniprot
Trinucleotide repeat-containing gene 6A protein