Terminology Service < Semantic Lookup Platform

All terms in BAO

Label	Id	Description
concentration endpoint	BAO_0000180	[It can refer to the screening concentration (for example in a primary assay) or it can be a concentration at which the perturbagen mediates a defined response, such as IC50 or EC50. It always has one value and a concentration unit.]
measure group	BAO_0000040	[Measure group is used to group and link multiple (different) sets of experimental results to one bioassay. Measure groups thus facilitate the description of multiparametric (or multiplexed) assays, that measure more than one effect of the perturbagen on the system that is screened. It also facilitate the definition of panel and profiling assays, e.g. assays that test compounds against multiple (protein) targets. Compare definition of bioassay. Measure group links to those classes that can vary among different measurements of a panel assay, profiling assay, multiparametric assay, e.g. target, assay design method, physical detection method, endpoint. Measure group is also used to define derived endpoints, for example concentration-response endpoints obtained by curve fitting a set of results from the same compound tested in the same assay at different concentrations.]
screening campaign	BAO_0000178	[Screening campaign incudes a sequence of (assay) experiments performed to identify a compound (or a series of compounds) with a specific function and it is desirable to have a known mechanism of action. It includes primary (screening at single concentration), secondary, and confirmatory (dose response) screens, structure activity relationship (SAR) studies, lead optimization, etc.]
experimental specification	BAO_0002933
small molecule	BAO_0000176	[Small molecule is an organic compound with a low molecular weight (<800 Da) which is used to screen against a biological target, e.g. protein, nucleic acid, cell or organism to test its ability to bind it and bring about a change in activity. It is either isolated from a natural source or is synthesized.]
screened entity	BAO_0000076
protein	BAO_0000175	[A protein or polypeptide is a long polymer of amino acids joined together by peptide bonds. The sequence of the amino acids is defined by the genetic code. Here, a protein is a perturbagen whereby its ability to modulate a physiological process or a disease pathology is assessed.]
protein preparation method	BAO_0000356	[This describes the method by which a protein is purified from its source.]
peptide	BAO_0000325	[Peptide is a short polymer of amino acids, which is generally <50 amino acids long.]
peptoid	BAO_0000174	[Peptoids are a class of biomimetic polymers based on oligo-N-substituted glycine backbones, designed to mimic peptides and proteins. Peptoids are resistant to proteolysis and not typically denatured by solvent, temperature, or chemical denaturants.]
ACTOne Membrane Potential Dye	BAO_0000172
dye	CHEBI_37958
transient arthritis	DOID_2092
arthropathy	DOID_381	[A bone inflammation disease that is located_in joint.]
vulvar melanoma	DOID_2093
vulva cancer	DOID_1245
sweat gland cancer	DOID_2095
sweat gland disease	DOID_1383
skin cancer	DOID_4159	[An integumentary system cancer located_in the skin that is the uncontrolled growth of abnormal skin cells.]
percent control	BAO_0000143	[Percent control is the response relative to a reference state, typically to a high control. For example it can describe (remaining) activity of a kinase (or e.g. kinase bound to substrate). Percent control could also quantify an inhibitory action depending on control and assay method.]