Terminology Service < Semantic Lookup Platform

All terms in BAO

Label	Id	Description
viability measurement method	BAO_0000127	[Compound cytotoxicity is an important parameter to measure when developing potential human therapeutics. Cytotoxicity is determined as a measure of radioisotope (3H thymidine or 51Cr) release, lactate dehydrogenase release from damaged cells, tetrazolium salt and alamar blue reduction, fluorescent dyes that selectively stain live or dead cells, and decrease in ATP content. The viability reporter technologies measure cell life or death by quantitating ATP content, caspase activity, membrane potential, and so on.]
phosphatidylinositol (3,4,5)-triphosphate	BAO_0002784
gene expression assay	BAO_0002785	[This assay quantifies the expression level of the entire gene pool in a cell or a subpopulation (e.g. tissue-specific gene expression, kinases) using either microarray, bead method, RNASeq, or reporter gene method.]
bioassay	BAO_0000015	[A set of instructions, methodology, operations, required reagents, instruments to carry out experiments for the purpose of testing the effect of a perturbing agent in a biological model system, measuring one or multiple effect(s) of the agent facilitated by an assay design method translate the perturbation into a detectable signal to arrive at one or multiple endpoint(s) that quantify or qualify the extent of the perturbation. Bioassay is described by multiple bioassay components: assay format, biology (biological participants in various role and processes), design method, physical detection method / technology, screened entity, and endpoint. Bioassay includes one or multiple measure groups to describe panel, profiling, multiparametric (or multiplexed) assays (assays that measure more than one effect of the perturbagen on the system that is screened).]
cell cycle state assay	BAO_0002786
cell cycle assay	BAO_0002041
reporter gene method	BAO_0000125	[Inducible reporter technologies involve the use of a reporter gene to study the effect of perturbagens on gene expression. Some reporter genes can be easily detected, e.g. green fluorescence protein, and others function as selectable markers, e.g. antibiotic resistance.]
gene expression detection method	BAO_0003024	[The technologies used to quantify the expression level of the entire gene pool in a cell or a subpopulation (e.g. tissue-specific gene expression, kinases pool, etc.) using one of the three methods, namely: microarray, bead based method or RNASeq.]
nonionic surfactant	CHEBI_38828
surfactant	CHEBI_35195
systemic acquired resistance inducing compounds	CHEBI_26842
xenobiotic	CHEBI_35703
neurotransmitter	CHEBI_25512
molecular messenger	CHEBI_33280
synthetic auxin	CHEBI_26841
auxin	CHEBI_22676
sodium-glucose transport protein subtype 2 inhibitor	CHEBI_73273
biochemical role	CHEBI_52206
adrenal gland disease	DOID_9553	[An endocrine system disease that is located_in the adrenal gland.]
endocrine system disease	DOID_28	[A disease of anatomical entity that is located_in endocrine glands which secretes a type of hormone directly into the bloodstream to regulate the body.]